Interview
John E. Abele, Part III


This week we continue our interview with John E. Abele, Founder Chairman of Boston Scientific Corporation. Mr. Abele began his involvement with the field of minimally invasive medicine over three decades ago. Today Boston Scientific Corporation is a worldwide leader in the manufacturing of devices for interventional cardiology and radiology.
 
John Abele

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Q: You mentioned that in the beginning a community of developers formed around Gruentzig. How did this community get started?


Gruentzig during early course
Andreas Gruentzig
having
a "blackboard"
discussion during an
early course in Zurich

Abele: In November of 1977, at the American Heart, he presented his first human case. It was kind of interesting because that case had been done only a month or two before. There was a standing room only audience and one of the few times I’ve been in any scientific publication when, after he showed his coronary and the cine of it, the audience stood up and gave him a standing ovation. Obviously tremendous recognition of this event.
 
That lead to an avalanche of people, this is ‘77 now, going over and visiting him in Zurich. These were sort of one at a time cases. But the difficulty was, he was kind of a lowly person in the hospital and having visitors come to the hospital all the time and crowd the cath lab was not looked upon favorably by his bosses. So he had sort of run out of his favors that he could ask, and the solution was, "why don’t I invite them all here at once?" That was the origin of the first course.
 
I guess there were two or three courses in Switzerland before he came to the U.S. I don’t remember the exact number, but the people who went to those courses sort of count themselves among the cognoscenti of the origins of angioplasty.
 
Attendees to the 1980 PTCA Course in Zurich
Attendees to the
1980 Zurich Course


 
party on the mountain
After the Course:
a Party and Torchlight
Mountain March


 
And in each course he created great fellowship among the attendees. They would go out and have their dinners and he would tend to do something very personal in nature, rather than what one might see now of going out to restaurants every night. In one of the most famous incidents, they had the trip up the mountain.
 
And the bonding obviously, as a result, was much stronger. There were both cardiologists and radiologists and even some surgeons who attended those courses. So it was a cross-fertilization as well as a bonding within the cardiology fraternity.
 
Q: Was the creation of this community intentional, premeditated, on the part of Andreas Gruentzig?
Abele: Yes. He felt that, if he was going to be successful, he had to have broad appreciation, not only for the procedure, but for the process by which it was developed. And exposing all the warts, as well as the successes along the way, was the best way to do that.
 
So, although operating theaters had existed for 100 years in which surgeons would watch the master at work, this was a very interesting spin-off of that, in which you had the live television and you had critics who were able to comment real time on what was going on in the procedure.
 
With the master, you know, you had to be careful about asking questions that questioned the skill or the integrity of the master. Gruentzig invited criticism, he invited questions and, because of his skill as a communicator and an educator, it was, you know, just a powerful experience for the audience.
 
Gruentzig at an early course
Gruentzig in an audience
discussion during an
early course (1980)


 
So he introduced not only angioplasty, but really the effective live demonstration course, which has migrated not only into other areas of cardiology, but really throughout medicine.
 
Gruentzig with early balloon catheter
Gruentzig shows an
early balloon catheter


 
Q: How did Gruentzig initially view the technique of PTCA?
Abele: He made no claims that this was going to be a panacea. He said he envisioned it being maybe suitable for five or ten percent of all patients. And as he developed the technique, and as others developed the technique, yes! The percentage increased. But he did it, stage by stage, rather than techniques that got involved with venture capital, for example, where they start out by saying, "This is a billion dollar business!", and somehow working up to that point.
 
Again, I think, the fact that his commercial connection was more of a modest one. He had a relationship with Schneider. But he would choose to go slow and to limit the circulation of the product — I mean that was unheard of in any development — so that he could control it and teach people. The idea of requiring that everybody who used the product had to have some counseling or education by him was also rather unique.
 
Q: Having known him before the technique became famous, what would you say were his prime motivations?
Abele: I’d be guessing here, but I know when my wife and I visited him in Zurich in ‘75, he lived in a very Spartan way, and appeared to feel strongly that this was an appropriate way to live. I would use the world "socialist", if I would go that far.
 
John E. Abele
John E. Abele
 
When he visited us in the States, he stayed in our house, and he criticized me for using paper cups (and probably quite correctly, but when you have a lot of kids, you know...). He would not use the dishwasher, he didn’t have a dishwasher, he’d just rinse them out in the sink, and that was the minimum amount of water. So I’m extrapolating a bit here, but I think he was motivated by discoveries for the benefit of mankind.
 
When you listen to him describe the value of the technique he was using, he was a very personally compassionate person. He did treat patients, not vessels. I think that’s something that sometimes is lost on modern day cardiologists.

 
Q: Could you expand on that — the idea of treating patients, not vessels?
Abele: You have to say, "Now what is the difference to the patient between the way in which [Gruentzig] was treating them and the way in which they would have been treated before?" Now let’s say the treatment before is an operation. The difference, a significant one, is it’s much less invasive.
 
Doctor with a Patient
Dr. Richard Myler
talks to an awake
patient during PTCA


 
But perhaps more important is that the patient is awake! So the patient is in fact a partner, or can be, depending on the physician, in his own, or her own treatment. I’ve always felt that that’s part of the holistic nature of successful therapy. Unless you get the patient in on the bargain, you’re not going to get the result that you hoped for.
 
I think you’re seeing more and more of that in today’s medical environment: the interest in alternative medicine, the interest in people understanding their own well-being, the diseases that they may have, the access to the Internet now.
 
The interest in medicine is just exploding and people are taking more responsibility and interest in their own health — both the well-being side of it and, if they have a disease, understanding it so they can treat it as a partner with the physician, as opposed to the "leave the driving to us" philosophy that has existed in the past.

 
Gruentzig with patient
Andreas Gruentzig
with a patient

Paret IV: John Abele's interview concludes with some observations on Gruentzig's legacy and its meaning for the world of medicine today.

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