This
week we continue our interview with John E. Abele, Founder Chairman
of Boston Scientific Corporation. Mr. Abele began his involvement
with the field of minimally invasive medicine over three decades ago.
Today Boston Scientific Corporation is a worldwide leader in the manufacturing
of devices for interventional cardiology and radiology.
 
Q:
You mentioned that in the beginning a community of developers formed
around Gruentzig. How did this community get started?
Andreas
Gruentzig
having a
"blackboard"
discussion during an
early course in Zurich
Abele:
In November of 1977, at the American Heart, he presented his first
human case. It was kind of interesting because that case had been
done only a month or two before. There was a standing room only audience
and one of the few times I’ve been in any scientific publication when,
after he showed his coronary and the cine of it, the audience stood
up and gave him a standing ovation. Obviously tremendous recognition
of this event.
 
That
lead to an avalanche of people, this is ‘77 now, going over and visiting
him in Zurich. These were sort of one at a time cases. But the difficulty
was, he was kind of a lowly person in the hospital and having visitors
come to the hospital all the time and crowd the cath lab was not looked
upon favorably by his bosses. So he had sort of run out of his favors
that he could ask, and the solution was, "why don’t I invite them
all here at once?" That was the origin of the first course.
 
I
guess there were two or three courses in Switzerland before he came
to the U.S. I don’t remember the exact number, but the people who
went to those courses sort of count themselves among the cognoscenti
of the origins of angioplasty.
 
Attendees
to the
1980 Zurich Course
 
After
the Course:
a Party and Torchlight
Mountain March
 
And
in each course he created great fellowship among the attendees. They
would go out and have their dinners and he would tend to do something
very personal in nature, rather than what one might see now of going
out to restaurants every night. In one of the most famous incidents,
they had the trip up the mountain.
 
And
the bonding obviously, as a result, was much stronger. There were
both cardiologists and radiologists and even some surgeons who attended
those courses. So it was a cross-fertilization as well as a bonding
within the cardiology fraternity.
  Q: Was the creation of this community intentional, premeditated,
on the part of Andreas Gruentzig? Abele: Yes. He felt that, if he was going to be successful, he
had to have broad appreciation, not only for the procedure, but for
the process by which it was developed. And exposing all the warts,
as well as the successes along the way, was the best way to do that.
 
So, although operating theaters had existed for 100 years in which
surgeons would watch the master at work, this was a very interesting
spin-off of that, in which you had the live television and you had
critics who were able to comment real time on what was going on in
the procedure.
 
With
the master, you know, you had to be careful about asking questions
that questioned the skill or the integrity of the master. Gruentzig
invited criticism, he invited questions and, because
of his skill as a communicator and an educator, it was, you know,
just a powerful experience for the audience.
 
Gruentzig
in an audience
discussion during an
early course (1980)
 
So
he introduced not only angioplasty, but really the effective live
demonstration course, which has migrated not only into other areas
of cardiology, but really throughout medicine.
 
Gruentzig
shows an
early balloon catheter
 
Q:
How did Gruentzig initially view the technique of PTCA? Abele: He made no claims that this was going to be a panacea. He
said he envisioned it being maybe suitable for five or ten percent
of all patients. And as he developed the technique, and as others
developed the technique, yes! The percentage increased. But he did
it, stage by stage, rather than techniques that got involved with
venture capital, for example, where they start out by saying, "This
is a billion dollar business!", and somehow working up to that point.
 
Again,
I think, the fact that his commercial connection was more of a modest
one. He had a relationship with Schneider. But he would choose to
go slow and to limit the circulation of the product — I mean that
was unheard of in any development — so that he could control it and
teach people. The idea of requiring that everybody who used the product
had to have some counseling or education by him was also rather unique.
 
Q:
Having known him before the technique became famous, what would you
say were his prime motivations? Abele: I’d be guessing here, but I know when my wife and I visited
him in Zurich in ‘75, he lived in a very Spartan way, and appeared
to feel strongly that this was an appropriate way to live. I would
use the world "socialist", if I would go that far.
 
John
E. Abele
 
When
he visited us in the States, he stayed in our house, and he criticized
me for using paper cups (and probably quite correctly, but when you
have a lot of kids, you know...). He would not use the dishwasher,
he didn’t have a dishwasher, he’d just rinse them out in the sink,
and that was the minimum amount of water. So I’m extrapolating a bit
here, but I think he was motivated by discoveries for the benefit
of mankind.
 
When you listen to him describe the value of the technique he was
using, he was a very personally compassionate person. He did treat
patients, not vessels. I think that’s something that sometimes is
lost on modern day cardiologists.
  Q: Could you expand on that — the idea of treating patients, not
vessels? Abele: You have to say, "Now what is the difference to the patient
between the way in which [Gruentzig] was treating them and the way
in which they would have been treated before?" Now let’s say the treatment
before is an operation. The difference, a significant one, is it’s
much less invasive.
 
Dr.
Richard Myler
talks to an awake
patient during PTCA
 
But
perhaps more important is that the patient is awake! So the patient
is in fact a partner, or can be, depending on the physician, in his
own, or her own treatment. I’ve always felt that that’s part of the
holistic nature of successful therapy. Unless you get the patient
in on the bargain, you’re not going to get the result that you hoped
for.
 
I
think you’re seeing more and more of that in today’s medical environment:
the interest in alternative medicine, the interest in people understanding
their own well-being, the diseases that they may have, the access
to the Internet now.
 
The interest in medicine is just exploding and people are taking more
responsibility and interest in their own health — both the well-being
side of it and, if they have a disease, understanding it so they can
treat it as a partner with the physician, as opposed to the "leave
the driving to us" philosophy that has existed in the past.
 
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