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Can A Total Occlusion Be Stented?

I recently had my first angiogram performed. It showed a 100% blockage in mid LAD. My Cadiologist said that he could not open this blockage with angioplasty and that surgical bypass would be necessary. Due to my health and age this would be rather risky. Anyone who knows if and where I could get angioplasty performed on this 100% blocked coronary artery please let me know.
B. Johnson, Texas, USA

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Current Postings on This Page (28):

• Dear Blocked -- Sorry, but you can't unimpress us! ;-)
Forum Editor, Angioplasty.Org, July 21, 2010

• Thank you for the direction. I have to clarify on the Mt Kilimanjaro trek it was a 1 day or 4 hours up and 2 hours down only climb up to approx 4000 meters, not the entire mountain!
blocked but not broken, Singapore, July 21, 2010

• Blocked But Not Broken -- your 100% blocked RCA is a CTO (Chronic Total Occlusion). These are very difficult to open and there is a relatively small group of interventional cardiologists who have the most experience in this area -- but it's still not always successful, and the results may not afford any immediate noticeable benefit (in fact a study was just published showing that opening CTOs may make help mollify the adverse effects of heart attack in another vessel, but may not lower the risk of one in the blocked vessel). However, you just climbed what??!! We'd wager that many with fully open coronary arteries would have difficulty climbing Kilimanjaro in one day. You may not be finding much information researching corollary arteries -- try looking up "collateral circulation" -- as far as testing collaterals, they can be seen on the angiogram, and a stress test would show if there is a perfusion deficit (reduced oxygen) to any part of your heart -- although it sounds like you just performed a stress test of sorts! Congratulations.
Forum Editor, Angioplasty.Org, July 21, 2010

• I was diagnosed with 100% blocked mid right coronary and 40% in the left, as of 12 months ago. My cardiologist was unable to clear block and stent after 90 minutes of plumbing. Now my burning question (to which have been unable to find relevant hits) is the aspect of Corollary development. Several anecdotal and verbal refs do exist to the corollary arterial development to support the blocked vessel. *** Is there a definitive test to determine the extent of corollary development?Never had angina, just climbed Mt Kilimanjaro (one day only:) regular swim, exercise, scuba etc.
blocked but not broken, Singapore, July 21, 2010

• Oakridges -- one of the big questions about the usefulness of trying to open a 100% blockage (CTO) is whether the part of the heart muscle supplied by that artery is still viable. If the heart muscle is dead, then opening the artery will do little. There was a study of CTOs just published in the American Heart Journal, and the co-author was Dr. Stéphane Rinfret of Laval University in Quebec City. Since you are in Canada, perhaps you can get some more specific advice from that institution.

And Mikestone in Israel, same thing about whether or not to open the CTO. And again, there are very few interventionalists who have achieved high success rates in this procedure, but you can find them with a little research.
Forum Editor, Angioplasty.Org, July 20, 2010

• I am 60 years old. 9 years ago I had a heart attack which resulted with a stent implant in my LAD. 3 years ago it was determined that the stent was totally occluded (CTO). By DAILY exercise (20 km. bike riding every morning) and extensive diet changes, I have been maintaining a full and active life WITHOUT a bypass (BTW I have been off the statins since 2003 due to the very negative side effects I had experienced). What is your opinion about attempting to open the CTO in my case?
mikestone, Israel, June 4, 2010

• My Dad had an angiogram which shows 2 arteries 100 blocked and the 3rd 90 percent blocked. Is there nothing that can be done to help him. He's on nitro but he needs to spray 4 -5 day. He has been told that he won't survive heart transplant. Has anyone gone through this and what worked for you. Even if we need to get this done in the US...please advise.
Oakridges, Ontario, Canada, June 2, 2010

• There is a physician in Bellingham, Washington named William Lombardi. He is currently doing a procedure to open a "CTO" Chronic Total Occlusion". He is using a new technology and he was able to open my CTO (in the right coronary artery) after two other cardiologists were unsuccessful. If you are interested please contact Cascade Cardiology in Bellingham, Washington (state). You may also find information on the web about Dr. William Lombardi.
Elissa O., Washington State, USA, April 22, 2010

• Prasugrel is a more potent antiplatelet drug than Plavix (clopidogrel) and therefore also carries a slightly higher risk of bleeding complications. But it is a good alternative if one is allergic to or resistant to Plavix. It was just approved for use in the U.S. in July 2009. Here's more info on Prasugrel from our Editor's Blog.
Forum Editor, Angioplasty.Org, January 10, 2010

• Hi I'm a 39 year old male and was diagnosed with a 100% Total Occlusion of the right coronary artery 2 weeks ago. 1 week later i have had 3 drug eluting stents put in. I considering myself very lucky. i Did have an reaction either to the contrast or the loading dose or subsequent week of taking plavix. A horrible skin rash which lasted 3 days. i am now on Effient. (Prasugrel Hydrochloride). My Cardiologist says that this is a slightly better drug. but is very new. Is there any links that can verify and give me more information Thank you.
Adam Weaver, Adelaide, South Australia, Australia, December 21, 2009

• Jenny -- did the doctors suggest bypass surgery?
Forum Editor, Angioplasty.Org, December 14, 2009

• I really need some input on my issue. My dad did the angiogram and found out his right branch of coronary artery is totally blocked and his two left branches of coronary arteries are 95% blocked and cardiologist told us he is not suitable to do the stent placement. In his situation, what can be done to save his life in this very well developed new technology world? Please help me out!!
Jenny, Boise, Idaho, USA, December 8, 2009

• I wanted to just comment on Mr B. Johnson, Texas, USA posting as I had the same problem. You didn't mention your age. Where as I was just 42 with highly sports activity & BMI 21 suddenly had 100% Occlusion in Lad its type III ostial stenosis. Actually it all depends on how quick you reach to a cardiologist after occlusion. I was told that if its with in just an hour enzymic treatment would do, if more than 2-3 hours needs intervention and as I had it for more than 8 hours before I recd a Primary PTCA with DES stent to LAD. But still I believe stent is no good to lead normal life except but when it is only option. Now a days newer technologies like motorized plaque cutter catheters and most sophisticated robotic surgeries are turning to be ideal All the best with good wishes for your speedy recovery...Er CVK Nageswara Rao
C V K Nageswara Rao, Avikanagar, Rajasthan, INDIA, October 4, 2009

• Workemail -- read below several entries that discuss "collaterals" -- a mesh-like grouping of small arteries that can form a bypass of a total occlusion. Usually the blood flow of these collaterals is less than a normal artery, but they may provide enough to avoid significant ischemia. Why the blocked artery wasn't bypassed is impossible to say without specific medical records, angiograms, etc. Stenting or angioplasty was probably not recommended because of his complex situation, although we daresay there are a number of interventional cardiologists who might have attempted it and met with success as well.
Forum Editor, Angioplasty.Org, July 10, 2009

• A close friend of mine's father just went in for triple by-pass surgery. They were only able to do a double due to one total blockage. The doctors told them, however, that the blocked artery had already rerouted itself so it had actually "fixed" itself. He is still in the hospital and isn't healing very well (infection). Would there have been another route they could have taken for him?
Workemail, Indianapolis, Indiana, June 30, 2009

• Jane G. -- from your post, we're assuming you have had bypass surgery, but we're unclear whether you've been looked at by an interventional cardiologist. Bypass surgery is done by cardiac surgeons; stenting and angioplasty is done by interventional cardiologists. These are two separate specialities, although they often work together. There are a number of expert cardiologists in the New York area who specialize in opening total occlusions (e.g. Columbia University Medical Center is part of a total occlusion summit held annually in NYC).
Forum Editor, Angioplasty.Org, June 29, 2009

• I have 100% blocked artery and live on the vein they took from my leg. And one other vein that is so weak and diseased that they could not put a stent in or anything. What can I do to unblock the arteries? Can you be good enough to help me?
Jane G., New York, USA, June 25, 2009

• Judy -- chronic total occlusions (CTO) are very challenging for the interventionalist to open -- there are a number who specialize in this, but the question (as with all procedures) is why do it? There is debate in the interventional medical community as to whether opening a CTO is necessary if collaterals have taken over much of the burden and the EF is in the near normal range. And, of course, how to successfully re-open the CTO. There are summits organized addressing just such issues. The question is whether your husband is having symptoms that can be resolved only through revascularization (re-establishment of blood flow, whether through angioplasty or bypass) -- or possibly whether his condition warrants a bypass to prevent a future event. These are complex questions, and much depends on the very specific clinical details of your husband's condition. We would suggest consulting both an interventional cardiologist AND bypass surgeon -- to get a sense of whether further procedures are necessary or helpful.
Forum Editor, Angioplasty.Org, May 20, 2009

• My husband had an angiogram showing 100% blockage of the LAD (yikes). Being an overweight, poorly controlled diabetic with labile hypertension, it was found he had had an MI with damage to anterior wall and apex and had not known it. Fortunately several collateral vessels had developed and evidently feeding the remaining muscle since his EF was 45%. The interventional cardiologist tried for 5 hours to open the blockage but was unsuccessful. The suggestion is that my husband have an off pump bypass. Is this bypass necessary even though there is some collateral circulation? Thank you.
Judy K., Texas, USA, May 19, 2009

• Trevor -- the re-opening (revascularization) of total occlusions is a specialized area of angioplasty and stenting. The big question is "how will re-opening the occluded artery affect the patient's clinical status". Often collaterals, small branches, form around the total occlusion forming what some call a "natural bypass". The success rate really depends on specific anatomical characteristics, and on the age of the occlusion. Obviously a chronic old calcified total occlusion is very difficult. Also total occlusions tend to restenose at a higher rate. But there are big debates on this subject within the cardiology community.
Forum Editor, Angioplasty.Org, March 10, 2009

• I'm finding it hard to find answers on stenting total occlusions. One of my arteries is 100% blocked and my cardiologist has booked me in to stent it. I know that stenting is pretty common, but is it common with total occlusions? Also, what is the success rate with stenting total occlusions? This is due to happen in three weeks, a quick response would be great.
Trevor, Australia, March 2, 2009

• At 53 I had a 95% circumflex artery blockage that was successfully stented. During the procedure they discovered the right coronary artery was 100% blocked at its base and was calcified. They could not get a wire through this calcification but there was good collateral circulation to that area of the heart. My question is how common is this? They do not wish to do a bypass or try to fix the RCA because the damage is already done. I still exercise daily but it takes me 10 minutes to warm up before I can do strenuous activities.
Leeg, British Columbia, Canada, August 31, 2008

• Marjory -- completely blocked arteries are called "total occlusions" and, if they have been blocked for some time, they are considered "chronic". If surgery is not possible in your case, you may want to consult an interventional cardiologist who specializes in Chronic Total Occlusions or CTOs. There are not many because this is a very difficult area, but not an unknown one. For instance, last month we attended a live demonstration course in New York where Dr. Shigeru Saito of Japan opened three total occlusions in one afternoon. He is one of the world's experts in this field. The Cardiology Research Foundation (they put on the big TCT interventional cardiology meeting in Washington every fall) has a special annual meeting devoted to CTOs. All this is by way of saying that CTOs are done, but by cardiologists who specialize in them. Perhaps contact the Montreal Heart Institute -- they are a major center and may have physicians who do CTOs.

Also it is very hard to evaluate a CTO with a standard angiogram, which shows a 2-dimensional "shadow" image of the arteries. Most cardiologists want to see a CT angiogram, or multislice CT, which gives much more detail about the occluded area (how long, whether the plaque is hardened, etc.). Finally, very often in such cases, the body manufactures collaterals, which are smaller arteries that deliver some blood flow. Good luck and let us know what you find out.
Forum Editor, Angioplasty.Org, May 4, 2008

• I have had an angiogram which shows 2 arteries 100 blocked and the 3rd 90 percent blocked. Is there nothing that can be done to help me. I am on .08 nitro patches during the day but at night I take them off but need my spray 3 or 4 times a night. I sleep sitting up. Am I really just waiting to die? Apparently I cannot have bypass as the arteries are so blocked there is nothing to sew the bypass onto. What about something to clean out the plaque somehow? I heard something about cold laser.
Marjory Sturgeon, Prescott, Ontario, Canada, April 27, 2008

• Did you find any solution of your problem? I have recently got my angiography and my LAD is also 100% blocked at two points. Two well known cardiologists have suggested angioplasty and they claim that they can handle the problem whereas 4-5 specialists have concluded that bypass is the only solution to the problem.
Tariq Mahmood, Pinstech, Pakistan, June 1, 2004

• My mother in law, who is 82 years old recently under went an angiogram which revealed 3 totally closed arteries and three partially closed arteries. What are her options?
Joseph Sartori, Colonial Beach, Virginia, USA, September 5, 2003

Are there any new techniques to get the guide wire through a chronic restenosed total occlusion in the RCA? One reason I was hoping this is the case, that the the August 5, 2001 article in Circulation by Dr Gregg W Stone regarding the new clot busting drugs prior to angioplasty improve results.
Besttt, September 14, 2001

LASER, special PTCA wires, sometimes Rotablators However, the clot busting drugs don't tend to work on chronic lesions such as the one you mentioned as they work on reasonably fresh clots. LASER wire is certainly an option, you need to find a centre that does it though! I hope this helps you
Andrina, Prince Sultan Cardiac Centre, Riyadh, Saudi Arabia, February 10, 2002

• I recently had my first angiogram performed. It showed a 100% blockage in mid LAD. My Cadiologist said that he could not open this blockage with angioplasty and that surgical bypass would be necessary. Due to my health and age this would be rather risky. Anyone who knows if and where I could get angioplasty performed on this 100% blocked coronary artery please let me know.
Burnett Johnson, Retired, Baytown, Texas, USA,, May 20, 2001

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