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Alternative to Angiogram?

Heart patients are given a number of different tests and some have questions whether the most invasive of these, the cardiac catheterization (a.k.a. angiogram) is necessary. Post these questions here. (More information about these tests can be found in Angioplasty.Org's "Imaging and Diagnosis Center".)

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Current Postings on This Page (32):

• Sam -- You might want to discuss a simple Calcium score test, which is a CT scan without contrast. It shows calcium buildup -- but that's all. Zero Calcium (or a very low score) would indicate low risk of coronary artery disease (CAD). But if the presence of CAD is already evident, as indicated possibly by the angina and CHF, then such a test would not be telling you very much that you don't already know. This is a difficult call, but it's one that needs to be made by specialists in this field, weighing the pros and cons of your uncle's specific clinical status and whether or not the angina can be controlled in other ways (medications, etc.).
Forum Editor, Angioplasty.Org, May 23, 2009

• My uncle is 73, CHF and CAD patient. Everything is well controlled until some recent increase in angina. His own cardiologist is reluctant to order an angiogram because of the Kidney risk. Some other hospital cardiologists brought up doing an angiogram, but the kidney risk seems like a major issue to all of them. My uncle's creatinine is slightly elevated (around 1.45), plus because of his CHF he is very volume restricted and, as I understand, effective hydration will not be possible in his case (as he could easily go into edema). What are the alternatives, while keeping the kidneys safe? I have seen an earlier answer with reference to less dye used for the CT - how much (volume) of dye is USED in CT? How much does the kidney risk go down? Any help would mean so much. Thanks.
Sam R., Vancouver, Canada, May 17, 2009

• I am 58 male. Had a DES placed last October. Prior to the placement, the cardiologist was able to due a non-invasive SCAN of my heart and found the blockage. I understand that now that the stent is placed, the test can not be done. Is anyone aware of any post Stent placement tests, scans that can be done short of going to the Cath Lab? thanks.
Lenny, Minnesota, USA, May 11, 2009

• Adams in Georgia -- nuclear stress tests have a relatively high false positive rate and many imaging specialists are now feeling that Cardiac CT, a.k.a. multislice CT angiograms, a.k.a. CCTA, are more accurate for diagnosing and/or excluding coronary blockages -- negative predictability of CT is in the 99% range -- meaning if the CCTA shows no blockage, you can be 99% sure it's correct. Without CCTA, you would probably have gone on to an invasive angiogram in the cath lab, with a 3% risk of complications.
Forum Editor, Angioplasty.Org, March 22, 2009

• I had a stress test and that showed a shady area - did the 64 slice CT showed 0 nothing -- said I had golden pipes.
Adams, Georgia, USA, March 20, 2009

• JC -- To answer your question, read the various interviews and news articles we have posted in our "Imaging and Diagnosis Center". These are decisions to be made between you and your cardiologist. The risks of a standard angiogram are small, but a CT angiogram (CTA) is a very accurate test for ruling out coronary artery disease and it carries virtually no risk. However, if your cardiologist believes you have a high likelihood of having a flow-limiting blockage, a catheterization with possible angioplasty is probably going to be required at some point, so a CTA won't add any information.
Forum Editor, Angioplasty.Org, September 13, 2008

• Lead up to flu caused heart like symptoms. EKG showed left branch blockage similar to 14 years ago but otherwise healthy heart. Did Nuclear stress this time. Stress portion went very well with no appreciable change in EKG at 174/? and 135 pulse after 7 1/2 minutes with no symptoms, 66% ejection rate. Pictures showed moderate blockage of artery leading to right chamber. Dr. want to follow up with cath. I am 61 and in good health but very anxious about risks associated with cath and am questioning whether to do it at all. Any thoughts on this?
JC, New York, USA, September 13, 2008

• Lorraine -- has your dad's cardiologist discussed the possibility of a non-invasive CT Angiogram (no catheter, done in a few minutes) to determine if he has a treatable blockage? He's on medical therapy, which works, but if he is still having symptoms which limit his activity, he, you and his cardiologist should talk.
Forum Editor, Angioplasty.Org, September 13, 2008

• Hi my dad had a triple bypass operation in 1989 (aged 50) and he made a good recovery within a couple of years, in 1998 he was advised to have an angiogram as some of his previous symptoms had reoccurred, under the angiogram he unfortunately suffered a stroke, from which he did make a good recovery, although it did leave some not so visible damage, the angiogram taken at that time did show that one of his arteries had a 90% blockage but because of the stroke the consultant choose to treat my dad with good medication, rather than do invasive surgery or angioplasty! He recently has had some of the reoccurring symptoms and is now 69 years old! Can you advise or give me any information to what are the alternatives to angioplasty, taken into consideration my dad's previous experiences?
Lorraine Offord, Leeds, UK, September 10, 2008

• Milda -- there are techniques that radiologists use to do studies (such as an MRA) where there is no or very diluted contrast used -- and also hydration techniques to lessen kidney damage. Keep asking questions until you find a radiologist who is familiar with these techniques.
Forum Editor, Angioplasty.Org, May 15, 2008

• My husband is currently on the inactive kidney transplant list. The doctors are requiring an angiogram prior to putting him on the active list. His nephrologist is telling him the dye will kill the kidney function he currently has (15%-18%). Would an MRA, or any other alternative procedure give the transplant doctors the information on his heart they require and get him on the active list.
Milda B., Ocean Park, Washington, USA, May 12, 2008

• Renuka -- in a patient such as your father, one who has a history of coronary artery disease, the standard invasive angiogram is usually the test of choice, since there is a high likelihood of finding a problem -- and a catheterization can be turned into an angioplasty if something obvious is found. Did the angiograms show any disease?? Iodinated contrast dyes, used both in catheterizations AND non-invasive CT scans, have been associated with kidney problems, and patients with low kidney function must be managed carefully for these types of tests, but we haven't seen any studies regarding an effect from dye on Potassium levels.
Forum Editor, Angioplasty.Org, March 16, 2008

• My dad has had a temp. pacemaker put due to low heart beat 29 . He is 71 and has already had a triple bypass 10 years ago. A heart attack a month back, an angiography 15 days ago and then this last week. All happening too fast. Potassium levels too rising. Could this be a result of the dye at the time of the angio or due to very strong medication. Had a kidney complete test done 3 months ago with all within range. Please clarify.
Renuka, Pune, India, March 14, 2008

• Cenia -- the tests you have had fall into two categories: the stress tests, whether nuclear or echo, are "functional tests" -- among other things, they measure whether or not the various parts of your heart muscle are receiving sufficient oxygen from the blood -- or how well your heart is "functioning", but they don't really visualize a blockage. The standard angiogram (or cath) actually images the arteries and any blockages can clearly be seen. A newer type of angiogram, done with multislice CT (called a CT Angiogram, or CTA), can also be done. Like the standard angiogram, it visually shows any blockages. But it is non-invasive (no cath lab) and takes about 15 minutes. It can carry a higher radiation dose than a cath, but the dose is equal to or less than a nuclear stress test. However, your cardiologist may want to do the stress test for specific reasons. Whether or not a CT angiogram would be useful for you is something you should discuss with your cardiologist.
Forum Editor, Angioplasty.Org, February 12, 2008

• Question about dense breast tissue and false positive/false negative nuclear scan. In 2006 I had an inpatient chemical stress test and a nuclear scan at a major heart hospital; the findings of which were various inconsequential blockages in the RCA and a major life-threatening blockage at the top of the LAD artery, so much so that I was not allowed out of bed until an angiogram could be done the next morning. The angiogram showed absolutely no blockage anywhere at all in the LAD and an 80% blockage at the top of the RCA which was stented. The false negative/false positive was blamed on dense breast tissue. Now I am due to have another stress test next week at my local cardiologist's office. He wants to do the nuclear scan and says he can take the previous issue into consideration, but I am doubtful and do not know what to do. How can my doctor know whether the results of the new scan--whatever it shows--will be trustworthy? I don't want a problem to go undiagnosed, and yet I wouldn't want to be sent for an angiogram unnecessarily. Would you please help me sort this out?
Cenia, New York, USA, February 12, 2008

• F/u to earlier post - My mother's aneurysm is in the heart (near the aorta I believe). Does this make a difference? Thanks for the info.
TD, Maryland, USA, February 11, 2008

• TD -- allergies to contrast dye are relatively specific but your concerns should be communicated clearly to the physician. You didn't mention where the aneurysm is located, but the answer is that an MRA may be an option -- there is a contrast agent sometimes used in MRAs, containing gadolinium, which has been implicated in a specific reaction in patients with impaired kidney function. But there are also techniques for performing MRAs without contrast. See our article on methods for doing contrast-free MRAs.
Forum Editor, Angioplasty.Org, February 11, 2008

• My mother was recently diagnosed with an aneurysm (via ultrasound). Now the Dr. wants to follow up with an angiogram to determine the nature/severity of the aneurysm. My mother is in relatively good health (for a 72-year-old) but she's extremely sensitive to meds and I'm concerned about the contrast dye. Would an MRA (mentioned above) be an appropriate alternative? If so, what are the risks with an MRA? Thanks in advance for your advice.
TD, Maryland, USA, February 11, 2008

• Jokhan -- read these posts. You could go for an angiogram, or get a multislice CTA which has been shown to be 99% accurate for negative results -- that is, if the CTA shows no coronary artery disease, you can be confident that there is none. And it's only 15 minutes, non-invasive and avoids the risks (although they are small) of the more invasive procedure.
Forum Editor, Angioplasty.Org, December 17, 2007

• Hi I am 30 yrs old male, having a healthy life. but Last week I felt little discomfort in my chest, somehow I got concern to meet a cardiologist. I met cardiologist, Dr suggested me for TMT. And TMT found +ve for inducible ischaemia, other things are negative. Dr's advise is, I can ignore it or I can go for angiogram for confirmation. Kindly suggest me what should I do, shall i go for angiogram?
Jokhan, Bengalore, India, December 12, 2007

• Tom -- CT Multislice and CTA are two names for the same procedure (see the Editor's Blog entry from yesterday about this -- "The Super X-Ray". Your question about whether or not CTA is equivalent to a standard invasive angiogram is most timely. The largest study yet on this subject was presented on Monday at the American Heart Association meeting (read our article about the CorE 64 Trial). CTA is pretty much an imaging mode to see structural data and blockages, not so much to measure flow, although some research on CT perfusion imaging is being done at Johns Hopkins. However, if your mother's cardiologist is concerned about blocked arteries, then CTA is an excellent test for ruling out blockages -- highly accurate (99%). We just conducted an interview with Dr. Michael Poon, president of the Society for Cardiovascular CT, and he stated that for patients where there is a question about blockages, but where the likelihood is low to intermediate, that's who CTA is for. Certainly I would ask the cardiologist more about CTA, especially for an elderly patient. The test takes 10 minutes and, outside of possible allergies to the contrast dye, there are no complications. But your mom's cardio may have good reasons why he wants the angiogram. Just make sure you understand what those reasons are.
Forum Editor, Angioplasty.Org, November 7, 2007

• How does a CT Multislice differ from a Coronary CTA? What are the pros and cons? Will either, or both, provide the cardiologist the same kind of diagnostic information as an angiogram? Why would my mother's cardiologist want to do the more invasive angiogram rather one of the less invasive procedures? She is almost 85 and is taking Betapace to control her atrial fibrillation. His concern seems to be centered on arterial flow from one part of the heart to another.
Tom F., Tucson, Arizona, USA, November 5, 2007

• I live near portland, oregon. My cardiologist who initiated the tests which led to my double bypass open heart surgery in june, 2006, says he wants to do another angiogram now. I don't want it, i want an alternative non-invasive procedure. What is available to me here? Who is the best known cardiologist in the Portland Or and greater Portland area who also uses non-invasive testing for 'blockage' due to sudden shortness of breath before they resort to invasive measures. I will be 68 this month. Type 2 diabetes, SLE patient but never have taken steroids, I refuse. At time of my stress test, the only part of testing which showing premature heartbeats, I had 6.8 potassium levels, a rarity for me who is usually low in potassium. My cardiologist is angry with me, but I need a 2nd opinion, where do I go please? Thank you for taking time.
Mary T., Myself fighting to live!, Oregon, USA, October 3, 2007

• Nancy -- an alternative to a cath, as you can see in this topic, is modern CT Angiography which, when done by experienced cardiologists or radiologists, can rule out the presence of coronary artery disease. The current state-of-the-art CT scanner would be a 64-slice unit. The test is fast (15 minutes), does not involve an arterial puncture and healing (just an IV for contrast injection) and is very accurate for ruling out narrowings. The downside is that contrast IS used (some people are allergic to contrast dye, some with compromised kidney function need to limit their exposure) although contrast is also used in a standard invasive angiogram. Also there is a degree of radiation exposure -- in modern systems, it's about the same or slightly more than an invasive angiogram. You can read more about the various tests used to diagnose CAD in our Imaging and Diagnosis Center. By all means, discuss this with your cardiologist. But it has been shown in several studies that If the multislice CT angiogram shows no disease, you can be confident that there is none and you can relax. When he said there was a "shady area" -- how did he see this -- what test??
Forum Editor, Angioplasty.Org, August 25, 2007

• My doctor said I had no symptoms but since I have anxiety attacks (thinking heart attack) he would go ahead and do a heart cath. He said one area was shady but he thought it could be where my heart is laying in my chest or the fact that I have large breasts - should I do the heart cath?
Nancy Adams, McDonough, Georgia, USA, August 22, 2007

• Tracey -- angiograms, both invasive (done in the cath lab) and multislice CT types require the use of a contrast dye for the imaging. An adverse effect of this dye is that it can cause toxicity if the kidneys are not functioning correctly -- it can even damage the kidneys. So the doctors are right in not wanting to use this until it can be determined that the kidneys are okay. There is a test that doesn't use dye -- called an MRA, or Magnetic Resonance Angiogram. These are less available than the CT or cath lab exams, mainly because not all hospitals have the equipment, or the personnel to interpret the MRA.

Once an Acute Myocardial Infarction (a.k.a."heart attack") is over, the main thing is to stabilize the patient, reduce any risk for another infarct and ultimately do an angiogram in a timely, but not emergency, fashion to assess the damage and to determine the course of treatment. And this treatment decision has recently changed: last year's OAT trial showed that opening up the totally blocked artery that caused a heart attack showed no benefit over drug therapy, once 3 or more days had passed -- which seems counter-intuitive, but the results were pretty clear. The recommended treatment for a heart attack is to do an angioplasty within the few couple of hours after the onset of symptoms, but this requires getting to a hospital that can perform emergency angioplasty quickly, and the hospital must be able to diagnose and get the patient onto the cath lab table ASAP (known as "door to balloon time"). By doing angioplasty quickly, the heart attack is in effect stopped and damage to the heart muscle is minimized. Let us know how your mother in law fares.
Forum Editor, Angioplasty.Org, June 6, 2007

• Hello! My mother in law is currently in ICU. She suffered what they have listed here as "Acute Myocardial Infarction with Acute Respiratory distress" her kidneys are not fully functional, but are coming around at a slow pace. Here is my question, the ICU MD wants her to have a angiogram but state they have to wait for her kidney function to recover. It has now been 3 days, she lay waiting. Is there any risk of her waiting for the angiogram? Is there an alternative test you could recommend in place of the angiogram? ICU MD's say they will not know the full damage until this angiogram is performed. Do you have any recommendations? All advice is greatly appreciated. Thank you for your time.
Tracey Thornton, Suisun, California, USA, June 6, 2007

• Nita -- your question is a bit off topic -- if there's interest, we'll start a new thread. Costs for procedures can vary quite a bit, depending on your hospital or testing center and at what level you're being tested. Also echocardiograms can vary in terms of how they are done and the different types -- for example is this a nuclear stress echo, an echo where adenosine or similar drug is used for patients who cannot perform the exercise? You also typically have a variety of charges: the echo itself, the interpretation of it, copies made for your cardiologist, etc. Our best suggestion is to call a few hospitals or test centers in your area and ask. For more information on the different tests used to determine coronary artery disease, go to our Imaging and Diagnosis Center.
Forum Editor, Angioplasty.Org, May 19, 2007

• What is the average cost for an Echogram? Thanks.
Nita, Texas, USA, May 17, 2007

• I have read that the average cost for an angiogram was $7,000.00 over 10 years ago. I have also read that a sonogram, ultrasound or echogram cost only a few hundred dollars. Is this information correct? Secondly, if an ultra sound test is usually step one, when and why is the angiogram, as a step 2, even needed? It's curious that I have never had a cardiologist want to do anything on me first but an angiogram and they never mention the ultrasound when I refuse the angiogram -- as I have always done. Finally, what percentage of angiograms actually trigger a blockage so that immediate invasive procedures must be taken to save the patient?
Gerald Oros, OrosCo Product Specialties, Collinsville, IL United States, October 30, 2005

• LaRee -- there are alternative tests for coronary artery disease, such as MSCT scans (read about them in our editor's Blog) that are less invasive. But if the functioning of the heart chambers is what's being looked at, then step one is usually an ultrasound, and then an angiogram. If you have questions as to whether any test is necessary, a good rule of thumb is always to ask, "How will this test change her current treatment?" If it won't, or if her ideal treatment can be found in other ways, then perhaps the test is not necessary. Any invasive procedure has risks, although percentage-wise, angiography complications are pretty low. But your cardiologist probably has specific reasons for ordering such a test. You should discuss the concerns expressed above with your doctor. And please let us know what you find out.
Forum Editor, Angioplasty.Org, October 15, 2005

• My mother is 83 years old, diabetic with many allegies. Her heart specialist would like her to have an angiogram because she seems to have undue pressure and enlargement in the right chambers of her heart. She gets along pretty well now and I am afraid that this procedure may cause more problems than it solves. Any information would be helpful in order to make an informed decision.
LaRee Spears, Benson, Arizona, USA, October 14, 2005


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• Multislice or Multidetector 64 Slice CT Angiogram

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