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Angiogenesis Overview

Angiogenesis is the body's natural response to ischemia. When part of an artery is blocked, smaller vessels begin to grow. For years, medical research has tried to harness this innate process to treat vascular disease. (Read more...)

The AWARE Trial (Angiogenesis in Women With Angina Pectoris Who Are Not Candidates for Revascularization) has just begun recruiting patients. The enrollment will only total 300 patients. If you are a woman who is experiencing angina, but you are not a candidate for angioplasty or bypass surgery, this trial may be of interest to you. Click here for a full description of the trial from the NIH web site.

NewsCenter: Reports and Features
Breaking news, original reporting and links to research on gene therapy for vascular disease. Featured stories:

Positive Findings on Generx Angiogenesis Therapy for Heart Disease Published in JACC (Sep 1)

Angiogenesis Therapy for Heart Disease Given Fast Track Designation by FDA (July 25)

Cardium Initiates Phase 3 AWARE Clinical Study; Patient Recruiting Begins (May 16)

Cardium Announces Automated Infusion System for Generx Phase 3 AWARE Study (April 17)

Cardium's Generx Advances to Phase 3 Following Meeting with FDA (Dec 7)

Discussion Forum
Still feeling angina after an angioplasty or other procedure? Share your stories about this and other topics.

Angioplasty.Org Interview with:
Randall W. Moreadith, MD, PhD

Randall W. Moreadith, MD, PhD		Dr. Moreadith is Executive V.P. and Chief Medical Officer of Cardium Therapeutics. Prior to joining Cardium, Dr. Moreadith served in a number of positions and companies in the fields of medicine, genetics, and biochemistry. He holds an M.D. from Duke University and a Ph.D. in Biochemistry from Johns Hopkins.

In this interview, Dr. Moreadith discusses the AWARE clinical trial (Angiogenesis in Women With Angina Pectoris Who Are Not Candidates for Revascularization), a Phase 3 randomized clinical trial for which he is principal investigator.

Also read the Angioplasty.Org Interview with: Robert L. Engler, MD
Dr. Engler has been a pioneer in the development of genetic and other innovations in the treatment of cardiovascular disease. In this interview, he explains how angiogenesis might solve the problem of angina and ischemia in patients who have persisent chest pain even after angioplasty or bypass surgery.		Robert L. Engler, MD

Click here to download Cardium's 48-page brochure, profiling the company's efforts in angiogensis with its Generx product, as well as other innovative therapies. (This sponsored content is being made available by Cardium Therapeutics.)

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