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Angiogenesis Overview

Angiogenesis is the body's natural response to ischemia. When part of an artery is blocked, smaller vessels begin to grow. For years, medical research has tried to harness this innate process to treat vascular disease. (Read more...)

NewsCenter: Reports and Features
Breaking news, original reporting and links to research on gene therapy for vascular disease. Featured stories:

Cardium Announces Agreement With bioRASI to Advance and Broaden Clinical Development of Generx Product Candidate (Feb 17)

Cardium Provides Update on Commercial Development Plans for Generx Angiogenic Therapy for Heart Disease at 2010 Cell and Gene Therapy Forum

Stent Pioneer Richard A. Schatz, M.D. Joins Cardium's Scientific Advisory Board (May 1 '08)

Cedars-Sinai Heart Institute in Los Angeles Now Enrolling Women With Recurrent Chest Pains For AWARE Clinical Trial (Mar 18 '08)

AWARE Clinical Trial Designed for Women with Heart Disease (Mar 13 '08)

Positive Findings on Generx Angiogenesis Therapy for Heart Disease Published in JACC (Sep 1 '07)

Angiogenesis Therapy for Heart Disease Given Fast Track Designation by FDA (July 25 '07)

Cardium Initiates Phase 3 AWARE Clinical Study; Patient Recruiting Begins (May 16 '07)

Cardium Announces Automated Infusion System for Generx Phase 3 AWARE Study (April 17 '07)

Discussion Forum
Still feeling angina after an angioplasty or other procedure? Share your stories about this and other topics.

Angioplasty.Org Interview with:
Prediman K. Shah, MD, FACC

Prediman K. Shah, MD		Dr. Shah is Director of the Division of Cardiology at Cedars-Sinai Medical Center in Los Angeles. He also is the Director of the Atherosclerosis Research Center of the Cedars-Sinai Heart Institute, where he leads several studies that focus on heart disease prevention and treatment.

In this interview, Dr. Shah discusses the AWARE clinical trial (Angiogenesis in Women With Angina Pectoris Who Are Not Candidates for Revascularization), a Phase 3 randomized clinical trial for which he is trial investigator at Cedars-Sinai

Also read the Angioplasty.Org Interview with: Randall W. Moreadith, MD, PhD
Dr. Moreadith is Exec. V.P. & Chief Medical Officer of Cardium Therapeutics. Dr. Moreadith has served in a number of positions and companies in the fields of medicine, genetics, and biochemistry. He holds an M.D. from Duke & a Ph.D. in Biochemistry from Hopkins.

Robert L. Engler, MD
Dr. Engler has been a pioneer in the development of genetic and other innovations in the treatment of cardiovascular disease. He discusses how angiogenesis might solve the problem of angina and ischemia in patients who have persisent chest pain even after PCI or bypass.

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